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Automated quantification and reconstruction of collagen matrix from 3D confocal datasets
55
Zitationen
8
Autoren
2003
Jahr
Abstract
The geometrical structure of fibrous extracellular matrix (ECM) impacts on its biological function. In this report, we demonstrate a new algorithm designed to extract quantitative structural information about individual collagen fibres (orientation, length and diameter) from 3D backscattered-light confocal images of collagen gels. The computed quantitative data allowed us to create surface-rendered 3D images of the investigated sample.
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