Enhancing clinical reasoning with Chat Generative Pre-trained Transformer: a practical guide

Abstract

Abstract Objectives This study aimed to elucidate effective methodologies for utilizing the generative artificial intelligence (AI) system, namely the Chat Generative Pre-trained Transformer (ChatGPT), in improving clinical reasoning abilities among clinicians. Methods We conducted a comprehensive exploration of the capabilities of ChatGPT, emphasizing two main areas: (1) efficient utilization of ChatGPT, with a focus on application and language selection, input methodology, and output verification; and (2) specific strategies to bolster clinical reasoning using ChatGPT, including self-learning via simulated clinical case creation and engagement with published case reports. Results Effective AI-based clinical reasoning development requires a clear delineation of both system roles and user needs. All outputs from the system necessitate rigorous verification against credible medical resources. When used in self-learning scenarios, capabilities of ChatGPT in clinical case creation notably enhanced disease comprehension. Conclusions The efficient use of generative AIs, as exemplified by ChatGPT, can impressively enhance clinical reasoning among medical professionals. Adopting these cutting-edge tools promises a bright future for continuous advancements in clinicians’ diagnostic skills, heralding a transformative era in digital healthcare.

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