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Multimodal GPT model for assisting thyroid nodule diagnosis and management
29
Zitationen
29
Autoren
2025
Jahr
Abstract
Although using artificial intelligence (AI) to analyze ultrasound images is a promising approach to assessing thyroid nodule risks, traditional AI models lack transparency and interpretability. We developed a multimodal generative pre-trained transformer for thyroid nodules (ThyGPT), aiming to provide a transparent and interpretable AI copilot model for thyroid nodule risk assessment and management. Ultrasound data from 59,406 patients across nine hospitals were retrospectively collected to train and test the model. After training, ThyGPT was found to assist in reducing biopsy rates by more than 40% without increasing missed diagnoses. In addition, it detects errors in ultrasound reports 1,610 times faster than humans. With the assistance of ThyGPT, the area under the curve for radiologists in assessing thyroid nodule risks improved from 0.805 to 0.908 (p < 0.001). As an AI-generated content-enhanced computer-aided diagnosis (AIGC-CAD) model, ThyGPT has the potential to revolutionize how radiologists use such tools.
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Autoren
Institutionen
- Artificial Intelligence in Medicine (Canada)(CA)
- Hangzhou Academy of Agricultural Sciences(CN)
- Zhejiang Cancer Hospital(CN)
- Chinese Academy of Sciences(CN)
- Hangzhou Cancer Hospital(CN)
- Zhejiang University(CN)
- Zhejiang Provincial Hospital of TCM(CN)
- Wenzhou Medical University(CN)
- Dongyang People's Hospital(CN)
- Jinan University(CN)
- Sun Yat-sen University Cancer Center(CN)
- Sun Yat-sen University(CN)
- Zhejiang Taizhou Hospital(CN)
- Taizhou Central Hospital(CN)
- Affiliated Hospital of Hangzhou Normal University(CN)