Clinical outcomes, learning effectiveness, and patient-safety implications of AI-assisted HPB surgery for trainees: a systematic review and multiple meta-analyses

Abstract

Introduction: Artificial intelligence (AI) applications are increasingly integrated into hepato-pancreato-biliary (HPB) surgery training, yet their impact on educational outcomes and patient safety remains unclear. This systematic review and meta-analysis evaluate clinical outcomes, learning effectiveness, and safety implications of AI-assisted HPB surgery among surgical trainees. Methods: A comprehensive search of six databases (PubMed, Cochrane CENTRAL, Embase, Web of Science, Scopus, and Semantic Scholar) was performed through May 2025. Studies involving surgical trainees utilizing AI-based platforms with measurable clinical, educational, or safety outcomes were included. Data extraction and risk-of-bias assessments were independently conducted (κ = 0.86-0.91). Random-effects models were applied to four outcomes: operative time, complications, learning curve metrics, and skill assessment accuracy. Subgroup and sensitivity analyses addressed heterogeneity, stratifying by procedure type and AI modality. Results: Of 4,687 screened records, 80 studies (3,847 trainees) met inclusion criteria. Four separate meta-analyses revealed: (1) operative time reduction of 32.5 min (MD -32.5, 95% CI: -45.2 to -19.8; I2 = 65%; 15 studies, 1,234 procedures); (2) decreased complications (RR 0.72, 95% CI: 0.58-0.89; I2 = 42%; 18 studies, 2,156 patients); (3) accelerated learning with 2.3 fewer cases to proficiency (SMD -2.3, 95% CI: -2.8 to -1.8; I2 = 55%; 10 studies, 423 trainees); and (4) AI skill assessment accuracy of 85.4% (95% CI: 81.2%-89.6%; I2 = 78%; 12 studies, 847 assessments). Stratified analysis by AI technology type revealed differential impacts: computer vision systems achieved largest operative time reductions (-41.2 min, 95% CI: -54.3 to -28.1), augmented reality showed -38.7 min (95% CI: -49.8 to -27.6), while machine learning demonstrated -24.3 min (95% CI: -32.1 to -16.5); test for subgroup differences P = 0.02. Subgroup analysis showed greater benefits for complex procedures (pancreaticoduodenectomy: -48.3 min) versus simple procedures (cholecystectomy: -18.4 min, P = 0.003). Complications showed similar procedure-specific patterns, with pancreaticoduodenectomy achieving RR 0.65 versus cholecystectomy RR 0.78. Critical View of Safety achievement improved from 11% to 78% (RR 2.84, 95% CI: 2.12-3.81). Publication bias was not detected (Egger’s test P > 0.05 for all outcomes). Discussion: AI-assisted HPB surgical training improves operative efficiency, reduces complications, enhances learning curves, and enables accurate skill assessment. These findings support systematic AI integration with standardized protocols and multicenter validation.

Ähnliche Arbeiten