Building AI-ready health systems: the AULSS6 (Padua, Italy) local health authority artificial intelligence implementation strategy.

Abstract

OBJECTIVES: To present the strategy developed by the Local Health Authority AULSS6, Padua Province, Italy, for implementing artificial intelligence (AI) in healthcare systems. METHODS: Between December 2024 and December 2025, a series of structured meetings of a multidisciplinary Steering Committee were conducted. Ideas, priorities and initiatives were systematically collected, categorized, and refined through consensus. RESULTS: The strategy produced several outcomes: an AI ethics and readiness checklist ensuring compliance with the EU AI Act, GDPR, (EU General Data Protection Regulation) and cybersecurity requirements; multi-level education programs for staff; systematic technology evaluation guidelines and HTA (Health Technology Assessment) evaluation studies planning; active participation in projects on AI for public health and clinical outcomes prediction and resource optimization; communication strategies designed to enhance transparency and trust. Collectively, these initiatives enabled AULSS6 to build institutional capacity for responsible AI adoption at the local level. CONCLUSIONS: AULSS6 shows that local health authorities can lead responsible AI implementation in healthcare. Its multidimensional approach close to the population offers a replicable, scalable model for health systems across Italy and Europe, advancing digital transformation through a bottom-up strategy close to the communities served.

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